Health Law Daily Wrap Up, CONTROLLED SUBSTANCES—FINAL RULES: DEA places O-DSMT in schedule I, (Aug 17, 2026)
By WK Editorial Staff
The DEA issued a temporary order to schedule O-desmethyltramadol, including its isomers, esters, ethers, salts, and salts of isomers, esters and ethers, in schedule I of the Controlled Substances Act.
The Drug Enforcement Administration (DEA) bases this action on a finding that placing O-desmethyltramadol (other names: O-DSMT; desmetramadol; 3-[(1R,2R)-2-[(dimethylamino)methyl]-1- hydroxycyclohexyl]phenol) in schedule I is necessary to avoid an imminent hazard to public safety. This order imposes the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances on persons who handle (manufacture, distribute, reverse distribute, import, export, engage in research, conduct instructional activities or chemical analysis with, or possess) or propose to handle O-DSMT (Final Rule, 91 Fed. Reg. 52013 (Aug. 12, 2026)).
Dates. The temporary order is effective August 12, 2026, until August 12, 2028.
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